Conclusion and References
The effects of aging on body composition, GH, and IGF-I secretion are variable, but distinct. Both GH- and IGF-I secretion decrease during aging, regardless physical exercising or calorie restriction. The optimal GH, and IGF-I levels for the elderly, regarding optimal metabolic situation and longevity are unknown. Therefore it is uncertain at this moment whether or not GH administration or stimulation of GH secretion by medication is beneficial to aging, but otherwise healthy individuals.
Aart J. van der Lely, Endocrinologist
Department of Internal Medicine
Division of Endocrinology
EMCR
40 Dr Molewaterplein
3015 GD Rotterdam
The Netherlands
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